A 21yr old male with Diabetic ketoacidosis with denovo detected DM with viral pyrexia

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A 21year old male resident of miryalaguda came to casualty with chief complaints of 
fever since 5 days, c/o decreased appetite since 7days, c/o vomiting  since 1day, c/o sob since morning.

Patient was apparently asymptomatic 5days back then he developed fever which was  insidious in onset, intermittent and was of  high grade type a/w chills and relieved on medication. Pt had h/o 1episode of vomiting 1day back which was non-bilious,non- projectile.
No h/o any burning micturition, throat pain, cold,cough.

PAST HISTORY:
Not a k/c/o HTN,DM, CAD, asthma, TB, epilepsy.

PERSONAL HISTORY:
Patient has mixed diet with normal appetite and adequate sleep. 
he has normal bowel movements and bladder filling. 
No addictions. 

No significant family history or allergic history. 

GENERAL EXAMNATION:
Patient is c/c/c ,moderately built and moderately nourished. 
No pallor, icterus, cyanosis, clubbing, lymphadenopathy, pedal edema. 
VITALS:
BP: 140/90 MMHG, 
PR: 120bpm 
Temp: 98.2°F, 
RR: 40 CPM, 
SPO2: 99% 

RS: BAE+,NVBS heard
CVS: S1 ans S2 heard. No murmurs.No thrills
P/A: soft and non-tender. 
CNS: No focal deformities. 

INVESTIGATIONS:
1) HEMOGRAM : 
Hb: 8.2
TLC: 15800
N:89
L:6
PCV: 30
Mcv:63.7
MCH:17.4
MCHC:27.3
PLC:3.37
RBC:4.71


2) LFT:
3)CUE
4)RBS:194 
5)BLOOD UREA:29
6)SERUM CREATININE:0.8 
7)URINE FOR KETONE BODIES:
8)ABG@2PM 

9)SERUM ELECTROLYTES @2pm
S.ELECTROLYTES@ 10PM 

10) Chest xray PA view: 

PROVISIONAL DIAGNOSIS:DIABETIC KETOACIDOSIS WITH DENOVO DETECTED DIABETES MELLITUS WITH VIRAL PYREXIA UNDER EVALUATION

TREATMENT: 
On DAY-1
1)NBM till further orders
2)IVF 3lit NS  @500ml/hr(in 3hrs) f/by IVF NS@250ml/hr 
3)Inj. HAI 4IU IV/stat f/b Inj. HAI 1ml (40IU) in 49ml NS @ 4ml/hr(untill ABG correction)
4)Inj. PAN 40mg IV/OD
5)IVF 5%DEXTROSE @50-100ml/hr(when GRBS <150) [increase/decrease acc. to GRBS]
6)Inj.OPTINEURON 1amp in 100ml NS/IV/OD 
7)GRBS monitoring hourly
8) Strict i/o. Monitoring
9)Inj. KCl 2amp in 500ml NS @100ml/hr

On DAY-2 :
SOAP NOTES:

S: 
No fever spikes,sob decreased ,no fresh complaints
O:
BP-110/90mm hg
PR-74bpm
CVS:S1S2 heard
Rs:BAE +,NVBS
P/A:soft
A:
HAGMA, DKA
Hemogram:
ABG @1AM

@8AM
@3PM

S.ELECTROLYTES:@8AM
@5PM
@10.30PM

P:
1)IVF 0.45% NaCl,RL @100ml/hr 
2)Inj. KCl 2amp in 500ml NS @100ml/hr
3)Inj. HAI 1ml (40IU) in 39ml NS @ 4ml/hr(untill correction of acidosis)
4)Inj. PAN 40mg IV/OD
5)Inj.OPTINEURON 1amp in 100ml NS/IV/OD 
6)GRBS monitoring hourly
7)Strict i/o. Monitoring
8)NBM till further orders


DAY-3 :
S: Patient sob decreased,No fresh complaints

O: BP 110/80 mm hg
PR: 70 bpm
CVS: s1 s2 heard 
RS: BAE+ NVBS 
P/A: soft 
ABG@6.30AM
S.ELECTROLYTES @8AM

Assesmemt : over night patient grbs around 290 mg/dl and Patient anion gap is reducing day by day and subjectively feeling better .

Plan of care : Look for today morning abg and stop iv insulin infusion and start him on NPH and HAI

DAY-4
Pt shifted to AMC
S: no fresh complaints

O: BP130/80 mm hg
PR 80 bpm
CVS: s1 s2 heard 
RS:BAE + NVBS 
P/A: soft,non tender

Assesmemt :  
DKA
GRBS 157mg/dl 
FBS :114 mg/dl
Hemogram:
HbA1c:
PLBS:
 
Plan : 
Stopped insulin infusion
Started Inj. NPH S/C according to grbs(8am---2pm---8pm)
Inj.HAI S/C acc to grbs
IVF NS,RL @100ml/hr
INJ.PAN 40mg

DAY-5
Pt shifted to ward
S: no fresh complaints

O: BP :110/80 mm hg
PR :102 bpm
CVS :s1 s2 heard 
RS:  BAE+,NVBS 
P/A: soft 

Assesmemt :  
DKA
GRBS 148mg/dl 
FBS:111 mg/dl

Plan : 
Started Inj. NPH S/C according to grbs(8am---2pm---8pm)
Inj.HAI S/C acc to grbs
Oral fluids
INJ.PAN 40mg
Thrombophobe ointment (l/a over left forearm)

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